maXis II

maXis II is the leader in QTOF technology with unprecedented performance in a wide range of applications to solve the most demanding analytical challenges.

Native samples, including antibody drug conjugates, can be measured at these enhanced performance levels (Native Mass Spectrometry).

Antibody Characterization – Intact and Subunit Analysis

Enhanced resolution and mass precision – for highly precise and accurate determinations of the monoisotopic masses of both the Light and Heavy Chains of mAb’s on an LC timescale for automated confirmation of product identity and detection of impurities. Superb raw data quality allows for fast and easy detection of modifications (including deamidation) in biotherapeutic characterization without the need for time and cost intensive digestion and peptide mapping of the entire antibody.

Native Mass Spectrometry (optional)

Enabled easier application of native MS for structural research of larger proteins and/or protein complexes (including antibody and drug conjugates).