VIP-HESI

VIP-HESI (Vacuum Insulated Probe Heated Electrospray Ionization) is a cutting-edge ion source designed to enhance sensitivity and optimize mass spectrometry (MS) analytical tasks. With its heated electrospray technology, VIP-HESI significantly increases ion yield, surpassing the capabilities of standard electrospray. This leads to a substantial gain in sensitivity for a wide range of compounds, making it an invaluable tool in metabolomics and pharmaceutical analysis, environmental analysis, food testing, and forensic drug investigations. With a proven track record as a robust workhorse ion source on Bruker TripleQuad mass spectrometers for nearly a decade, VIP-HESI has become an industry favorite.

One of the significant advantages of VIP-HESI is its compatibility with a wide range of instruments. The latest version can be used with all timsTOF and series instruments and can be quickly and easily installed.

The enhanced performance, the VIP-HESI system offers the microFlow emitter as an optional addition to its standard ESI sprayer. This simple drop-in replacement boasts an inner diameter of 50µm, significantly improving peak intensities within the lower flow range limits of the VIP-HESI source (ranging from 1µL/min to 50µL/min).

In the VIP-HESI system, an electrospray is maintained at a precisely controlled vaporizing temperature. This enables the analyte ions to undergo enhanced desolvation, even at high eluent flow rates during UHPLC separations, resulting in sharp chromatographic peaks.